Lhermitte-Duclos disease and pregnancy
نویسندگان
چکیده
Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) is a rare disorder, characterized by a slowly progressive unilateral neoplastic mass of the cerebellar cortex. The histopathological findings of LhermitteDuclos disease (LDD) include the widening of the molecular layer, which is occupied by abnormal ganglion cells, absence of the Purkinje cell layer and hypertrophy of the granulan cell layer. Magnetic resonance imaging (MRI) is a diagnostic modality of choice and reveals a characteristic non-enhancing gyriform pattern with the enlargement of cerebellar folia. The lesion is hypointense on T1and hyperintense on T2-weighted magnetic resonance images.1 In patients with a posterior fossa tumour suggestive of a dysplastic gangliocytoma on neuroimaging studies, a pathologic confirmation is necessary.2 Dysplastic cerebellar gangliocytoma is commonly associated with the progressive mass effect in the posterior fossa and is typiRadiol Oncol 2006; 40(1): 17-21.
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